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«Co-trimoxazole» brand is the British Approved Name. In other countries Bactrim has been marketed under many trade names, for example, such as Septra.



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Bactrim is a mixed type antibiotic. It consists sulfamethoxazole and trimethoprim. It used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, and Pneumocystis carinii pneumonia.

Generic Bactrim contains a mix of sulfamethoxazole and trimethoprim. This drug is supplied in tablets and a liquid suspension. Sulfamethoxazole and trimethoprim are both antibiotics that treat different types of infection caused by bacteria.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Bactrim will not treat a viral infection such as the common cold or flu. This product may also be used for other purposes not listed in this medication guide.


Cheap Bactrim 480 mg acts as a false-substrate inhibitor of dihydropteroate synthetase. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bactrim (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, Bactrim (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. This product, given at a common clinicaldosage, increased the phenytoin half-life by 39% and decreased the phenytoin metabolic clearance rate by 27%. Trimethoprim acts by interfering with the action of bacterial dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid.

Sulfonamides such as sulfamethoxazole are analogues of p-aminobenzoic acid (PABA) and are competitive inhibitors of the enzyme; inhibiting the production of dihydropteroic acid.

Bactrim Antibiotic

This drug is a synthetic antibacterial combination drug available in DS (double strength) tablets.

Drug may inhibit the hepatic metabolism of phenytoin. When administering these drugs concurrently, one should be alert for possible excessive phenytoin effect. There have been reports of marked but reversible nephrotoxicity with coadministration of this medication and cyclosporine in renal transplant recipients. Increased digoxin blood levels can occur with concomitant Bactrim therapy, especially in elderly patients. Serum digoxin levels should be monitored. If you miss a dose of Bactrim, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Folic acid is an essential precursor in the de novo synthesis of the DNA nucleosides thymidine and uridine.

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Take this drug exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Sulfonamides can also displace methotrexate from plasma protein binding sites and can compete with the renal transport of methotrexate, thus increasing free methotrexate concentrations.